Gordon Brush's medical applicator brushes are autoclavable for cleanroom, sterile environment, and medical applications. They are offered with a choice of either a premium-quality stainless steel tube or acetal, pencil-shaped handle. The stainless steel tube is clamped down on the fill material using five tons of pressure. Fill material choices with the stainless steel handle include: nylon, stainless steel wire, PTFE and PEEK. Acetal plastic handle applicator brushes are made using an epoxy-set Nylon fill. The NAD brush series is made with a high-temperature resistant adhesive that is autoclavable. These brushes meet FDA 21 CFR 177.2480 and ASTM D6100 standards and are RoHS 3 (2015/863/EU) compliant.